Description
Hypothesis
- Mean of physiological and clinical features change differently over time in 4 primary groups - txp_pos, non_pos, txp_neg, non_neg. Our goal is to quantify the difference statistically.
Interpretation
- If linear regression assumptions holds, the departure of confidence interval of feature mean conditioned/given a certain time in 4 groups reviews “significant” difference in time trend of feature mean in 4 groups.
Data
- time window
- (-24h,24h) around a blood culture
- 48h window around an observation in a patient’s safe zone which has most number of data available
- Imputation